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Correlation of single fibre EMG and muscle histochemistry using an open biopsy recording technique

Authors
Journal
Journal of the Neurological Sciences
0022-510X
Publisher
Elsevier
Publication Date
Volume
31
Issue
3
Identifiers
DOI: 10.1016/0022-510x(77)90215-5
Disciplines
  • Chemistry

Abstract

Abstract Single fibre electromyographic (SFEMG) recordings were carried out during open muscle biopsy. Nine patients were studied, including 5 with Duchenne muscular dystrophy, 2 with spinal muscular atrophy and 1 each with limb-girdle dystrophy and myotonic dystrophy. Correlations were possible between the SFEMG fibre density determinations and histochemical evidence of grouping in some biopsies, particularly involving Type I fibres. This combined technique permits an improved assessment of the functional state of abnormal muscle.

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