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Fatal encephalopathy in acute poisoning with organophosphorus insecticides:A clinico-pathologic study of two cases

Authors
Journal
Clinical Neurology and Neurosurgery
0303-8467
Publisher
Elsevier
Publication Date
Volume
81
Issue
4
Identifiers
DOI: 10.1016/0303-8467(79)90029-5
Disciplines
  • Biology
  • Medicine

Abstract

Abstract The clinico-pathologic findings in two patients with an acute organophosphorus intoxication, who died from an atypical central neurologic disorder, are presented. The necropsy showed severe hemorrhagic necrosis of the walls of the third and of the fourth ventricles, resembling lesions observed in severe forms of Wernicke's encephalopathy. The pathogenesis of this unusual complication is discussed.

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