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Detection of adenovirus type41 in stool samples by a latex agglutination method

Authors
Journal
Journal of Immunological Methods
0022-1759
Publisher
Elsevier
Publication Date
Volume
127
Issue
2
Identifiers
DOI: 10.1016/0022-1759(90)90073-5
Keywords
  • Detection Of Enteric Adenovirus
  • Adenovirus Type 41
  • Latex Agglutination Method

Abstract

Abstract We have developed a simple agglutination (LA) method for the detection of enteric adenovirus (EAd) in stool samples from infants with acute gastroenteritis. Ad type 41 (Ad41) was detected with high sensitivity and specificity by a slide agglutination test using latex particles coated with antiAd41 antibody (LA-antiAd41). The agglutination of LA-antiAd41 with Ad41 on a glass slide was evident macroscopically within 2 min. The sensitivity of the LA method was four times higher than that of the EM method.

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