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Oncogenes in neural tumors

Authors
Journal
Trends in Neurosciences
0166-2236
Publisher
Elsevier
Publication Date
Volume
9
Identifiers
DOI: 10.1016/0166-2236(86)90051-2

Abstract

Abstract Tumors result in part from somatic mutations that convert normal cellular genes (proto-oncogenes) to oncogenes. A powerful approach to understanding tumorigenesis is first to identify oncogenes, and then to determine how the products of these genes differ functionally from their counterparts in normal cells. In this article we will focus on the possible role of such genes in tumors of the nervous system and in normal neural development.

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