Abstract Friction and wear behavior of new nanomaterial-inorganic fullerene-like (IF) WS2 supramolecules has been compared with layered solid lubricants MoS2 and WS2. Lubrication mechanism of IF nanoparticles and tribochemistry of contact have been studied. The main advantages of IF nanoparticles lies in their round shape and the absence of dangling bonds. Velocity accommodation modes under friction with solid lubricant powders were considered. The main lubrication mechanism of contact with IF nanoparticles appears to be rolling friction.