Affordable Access

Publisher Website

Loss of an adrenergic effect in swiss mice

Authors
Journal
European Journal of Pharmacology
0014-2999
Publisher
Elsevier
Publication Date
Volume
38
Issue
2
Identifiers
DOI: 10.1016/0014-2999(76)90342-3
Keywords
  • β-Adrenergic Responsiveness
  • Hyperglycemia
  • Eosinophilia
  • Adrenergic Sensitivity
  • Biochemical Variation
Disciplines
  • Chemistry
  • Medicine

Abstract

Abstract The effect of adrenaline on the amount of blood eosinophils (eosinophilia) which had been found in Swiss mice in earlier experiments was lost after a few generations. The hyperglycermic response to adrenaline had not been changed. Sensitivities to noradrenaline and adrenaline were as found earlier, but the sensitivity to isoprenaline was reduced. The reduction of β-adrenergic responsiveness suggests variations in biochemical parameters of mice or the appearance of mice genetically less responsive to β-adrenergic drugs in only a few generations.

There are no comments yet on this publication. Be the first to share your thoughts.

Statistics

Seen <100 times
0 Comments

More articles like this

Loss of an adrenergic effect in swiss mice.

on European Journal of Pharmacolo... August 1976

Effect of host weight loss on Friend leukemia viru...

on Proceedings of the Society for... 1965
More articles like this..