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Factors affecting on the mental development in children with Congenital Hypothyroidism

Authors
Journal
International Journal of Pediatric Endocrinology
1687-9848
Publisher
Springer (Biomed Central Ltd.)
Publication Date
Volume
2013
Identifiers
DOI: 10.1186/1687-9856-2013-s1-p147
Keywords
  • Poster Presentation
Disciplines
  • Medicine

Abstract

Factors affecting on the mental development in children with Congenital Hypothyroidism POSTER PRESENTATION Open Access Factors affecting on the mental development in children with Congenital Hypothyroidism Nguyen Phu Dat1*, Van Lam Tra1, Vu Chi Dung2, Bui Phuong Thao2, Can Thi Bich Ngoc2, Nguyen Ngoc Khanh2, Nguyen Thi Hoan2 From 7th APPES Biennial Scientific Meeting Nusa Dua, Bali. 14-17 November 2012 Congenital hypothyroidism (CHT) is a common endo- crine disease in children. The disease should be moni- tored and required longlife hormone replacement therapy. Is necessary to assess the metal status and affecting factors to help in management and long-term follow-up for children with CHT. So we review the fac- tors which affect the mental development in children with CHT. The study recruited 70 children who were diagnosed CHT in National Hospital of Pediatrics from August 2001 to August 2011. It was a descriptive and cohort study. In this study, children were treated before 3 months of age have mental development as well as healthy children at the same age. In children diagnosed and treated between 3 months to <12 months of age, the risk of mental retardation was increased by 13.5 times. If treatment from 12 months to < 60 months of age, the risk of mental retardation was greater than 28. 8 times. If treatment after 60 months of age, the risk was 64 times higher than that of healthy children. Children without adherence to CHT medication had 4.1 times higher risk of mental retardation compared to children with adherence of CHT medication. These results suggest that the factors affecting CHT treatment outcomes were early diagnosis and treatment as well as treatment adherence. Authors’ details 1Ha Noi Medical University, Hanoi, Vietnam. 2National Hospital of Pediatrics, Hanoi, Vietnam. Published: 3 October 2013 doi:10.1186/1687-9856-2013-S1-P147 Cite this article as: Dat et al.: Factors affecting on the mental development in children with Congenital Hypothyroidism. Internatio

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