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Mechanical ventilation of infants of less than 1,501 gm birth weight: Health, growth, and neurologic sequelae

Authors
Journal
The Journal of Pediatrics
0022-3476
Publisher
Elsevier
Publication Date
Volume
88
Issue
4
Identifiers
DOI: 10.1016/s0022-3476(76)80001-7
Disciplines
  • Medicine

Abstract

A two-year follow-up study of 73 low-birth-weight (<1,501, gm) infants treated with positive pressure ventilation as neonates revealed the following: 24% incidence of lower respiratory tract infections during the first year; weight and height at two years averaging between tenth and twenty-fifth percentiles, major neurologic defects diagnosed in 14 boys (39%) and seven girls (18%); 35 children (48%) with one-year Bayley scores of less than 80. Major neurologic sequelae were closely associated with a neonatal history of seizures and intracronial hemorrhage and were more common in boys, survivors weighing more than 1,000 gm and following high-risk pregnancies.

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