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Temperature-sensitive mutants of human cytomegalovirus: Isolation and partial characterization of DNA-minus mutants

Authors
Journal
Virology
0042-6822
Publisher
Elsevier
Publication Date
Volume
84
Issue
1
Identifiers
DOI: 10.1016/0042-6822(78)90238-6
Disciplines
  • Physics

Abstract

Abstract Fifteen is mutants of human cytomegalovirus which are unable to form normal plaques at 39° but which do form plaques at 34° have been isolated following mutagenesis by ultraviolet light. Five mutants defective in viral DNA synthesis at 39° were classified into two complementation groups, A and B, normal and defective in the induction of viral DNA polymerase, respectively.

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