Affordable Access

Publisher Website

Primary cutaneous myxoid melanoma: Immunohistologic clues to a difficult diagnosis

Authors
Journal
Journal of the American Academy of Dermatology
0190-9622
Publisher
Elsevier
Publication Date
Volume
30
Issue
2
Identifiers
DOI: 10.1016/s0190-9622(94)70035-4
Disciplines
  • Biology
  • Chemistry
  • Medicine

Abstract

Abstract We describe a 25-year-old man with a primary cutaneous myxoid malignant melanoma and xeroderma pigmentosum. Histologically, the tumor had a lentiginous intraepidermal component and a dermal myxoid nodule containing fusiform cells with hyperchromatic nuclei and nuclear pseudoinclusions. Immunohistochemically, the tumor cells were positive for S-100 protein in both the epidermis and the dermis and did not stain with HMB-45, AE1-AE3, MNF 116, antiactin, or anti-p53 protein. Although this tumor is rare, it should be considered in the differential diagnosis of cutaneous myxoid lesions.

There are no comments yet on this publication. Be the first to share your thoughts.