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Experimental protection by a luteinizing hormone-releasing hormone agonist of a bone marrow nitrosourea aplasia. Preliminary observations

Authors
Journal
Cancer Letters
0304-3835
Publisher
Elsevier
Publication Date
Volume
25
Issue
2
Identifiers
DOI: 10.1016/s0304-3835(84)80036-1

Abstract

Summary d-Tryptophan-6-luteinizing hormone-releasing hormone (D-Trp6-LH-RH) applied from day −8 to day +15 before and after administration of the nitrosourea analog, N,N′-bis[ N-(2-chloroethyl)-N-nitrosocarbamoyl] cysteamine (CNCC), favored bone marrow restoration, as independently evaluated by 3 observers in a double-blind fashion.

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