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Crayfish vas deferens: Contractions in response tol-glutamate and gamma-aminobutyrate

Authors
Journal
Comparative and General Pharmacology
0010-4035
Publisher
Elsevier
Publication Date
Volume
2
Issue
5
Identifiers
DOI: 10.1016/0010-4035(71)90073-5

Abstract

Abstract 1. 1. The isolated crayfish vas deferens is highly specific and sensitive for l-glutamate (threshold approximately 10 −6 g. per ml), giving a phasic contraction. 2. 2. Rapid desensitization may explain the phasic nature of the contraction. 3. 3. The organ contracts tonically to γ-aminobutyrate (GABA). 4. 4. Other potential transmitter substances are without effect, so the vas deferens may contain only GABA and l-glutamate receptors.

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