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Infantile bullous pemphigoid treated with intravenous immunoglobulin therapy

Authors
Journal
Journal of the American Academy of Dermatology
0190-9622
Publisher
Elsevier
Publication Date
Volume
57
Issue
6
Identifiers
DOI: 10.1016/j.jaad.2007.08.005
Disciplines
  • Medicine

Abstract

A 3-month-old boy presented with a 2-week history of rapidly spreading skin rashes. Physical examination revealed generalized urticarial plaques with tense bullae and small vesicles. Histologic examination and immunofluorescence established the diagnosis of bullous pemphigoid. The disease was resistant to conventional therapies with the combination of corticosteroids, dapsone, and erythromycin. Finally, intravenous immunoglobulin therapy brought about a remarkable improvement. We suggest that intravenous immunoglobulin therapy is a valuable treatment option for intractable bullous pemphigoid in infants as well as in adults.

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