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A preliminary communication isolation and positive confirmation of chlordecone in rabbit oviductal fluid

Authors
Journal
Fundamental and Applied Toxicology
0272-0590
Publisher
Elsevier
Publication Date
Volume
3
Issue
2
Identifiers
DOI: 10.1016/s0272-0590(83)80065-7

Abstract

Abstract Chlordecone (10 mg/kg, sc in corn oil) was administered to mature female rabbits once daily for five days. Analysis of oviductal fluid collected from these rabbits over the course of this experiment confirmed the presence of chlordecone. It is reasonable to suggest that chlordecone may reduce mammalian fertility during the preimplantation period by producing deleterious effects on respective gametes and/or the embryo. The mechanisms by which chlordecone may interfere with fertilization and reproduction is discussed.

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