Abstract Combination tests involving both constant strain-rate deformation and creep have been carried out on single crystal Ni 3Al(Ta 0.5%) with compression axis [15 5 1̄]. Specimens were pre-strained 3% at constant strain-rate (∼ 10 −4 s −1) at room temperature (RT) and at 520°C (just below the peak temperature of flow stress vs temperature T p) respectively. Subsequently, both pre-strained specimens were subjected to creep at the same stress level, 330 MPa, and temperature, 520°C. After the combination tests, slip trace analysis was performed and dislocation structures were examined by transmission electron microscopy (TEM). The results suggest that not only pre-creep strain, but also the temperature of pre-creep deformation, affect the subsequent creep. It was found that specimens pre-strained at room temperature had a lower creep resistance while those pre-strained at 520°C had a higher resistance than virgin specimens crept under the same conditions, although the operative slip systems were the same and quite similar dislocation structures were observed.