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Prostate cancer: histopathological analysis of 66 cases

Authors
Journal
Infectious Agents and Cancer
1750-9378
Publisher
Springer (Biomed Central Ltd.)
Publication Date
Volume
6
Identifiers
DOI: 10.1186/1750-9378-6-s1-a4
Keywords
  • Poster Presentation
Disciplines
  • Biology
  • Medicine

Abstract

Prostate cancer: histopathological analysis of 66 cases POSTER PRESENTATION Open Access Prostate cancer: histopathological analysis of 66 cases Olabode Peter Oluwole1*, Abdulrahuaman Umar Murkthar2, Chinwuba Amaechina3 From The Science of Global Prostate Cancer Disparities in Black Men Jacksonville, FL, USA. 27-29 August 2010 Background In the United States and Europe, prostate cancer is the most common male malignancy and the second leading cause of cancer death after lung cancer. However, in spite of under-estimation and reporting of cancer bur- den in Pathology-based cancer registries in the develop- ing countries; prostate cancer is now ranked among the emerging male malignancy. Objective To demonstrate that prostate cancer is common among Nigerian males. Materials and methods This is a 5-year retrospective histopathological analysis of prostate cancer diagnosed between January 2005- December 2009 in the Department of Pathology, Uni- versity of Abuja Teaching Hospital, Gwagwalada, Abuja. The tumours were classified based on WHO classifica- tion of Prostatic tumours. Histological grading was done using Gleason grading system. Results Sixty-six (66) cases of prostate cancer were reviewed. The age range was between 40-89 years with a mean of 64.5 years. There were two bimodal age peaks at the seventh and eighth decades respectively. The surgical procedures were Trucut biopsies 64 (96.9%) and prosta- tectomy 2 (3.1%). The Gleason scores range from 2 to 10. Three (4.5%) patients were seen before the age of 50 years. There were 9 (13.6%) cases of well differentiated, 37 (56.0%) cases of moderately differentiated and 20 (30.4%) cases of poorly differentiated adenocarcinoma. No other histological types were seen. Conclusion In this study, there were bimodal age peaks of prostate cancer at the sixth and seventh decades, while moder- ately differentiated adenocarcinoma is the most com- mon presentation. Author details 1Department of Pathology, College of Health Sciences, Un

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