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Kinin B2 receptor regulates chemokines CCL2 and CCL5 expression and modulates leukocyte recruitment and pathology in experimental autoimmune encephalomyelitis (EAE) in mice.

Authors
  • 1
Type
Published Article
Journal
Journal of Neuroinflammation
1742-2094
Publisher
Springer (Biomed Central Ltd.)
Publication Date
Volume
5
Pages
49–49
Identifiers
DOI: 10.1186/1742-2094-5-49
PMID: 18986535
Source
Medline

Abstract

Our results suggest that B2 receptors have two major effects in the control of EAE severity: (i) B2 regulates the expression of chemokines, including CCL2 and CCL5, and (ii) B2 modulates leukocyte recruitment and inflammatory lesions in the CNS.

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