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Effects of chloralose-urethane anesthesia on single-axon reciprocal Ia IPSPs in the cat

Authors
Journal
Neuroscience Letters
0304-3940
Publisher
Elsevier
Publication Date
Volume
94
Issue
3
Identifiers
DOI: 10.1016/0304-3940(88)90033-x
Keywords
  • Motoneuron
  • Inhibitory Postsynaptic Potential
  • Muscle Spindle
  • Spinal Reflex
  • Chloralose
  • Urethane
  • Spinal Cord

Abstract

Abstract Reciprocal Ia inhibitory postsynaptic potentials (IPSPs) generated by single afferents have been recorded with signal averaging in unanesthetized ischemic-decapitate cats for comparison with measurements previously obtained from preparations anesthetized with a mixture of chloralose and urethane. The results are similar to those which we obtained recently for single-axon recurrent IPSPs. Together, the studies show that chloralose-urethane anesthesia has a depressant effect on two widely studied circuits in the mammalian spinal cord.

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