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Thiadiazine Derivatives as Antiprotozoal New Drugs

Authors
Journal
The Open Medicinal Chemistry Journal
1874-1045
Publisher
Bentham Science
Publication Date
Volume
5
Identifiers
DOI: 10.2174/1874104501105010051
Keywords
  • Article
Disciplines
  • Chemistry

Abstract

The 3,5-disubstituted tetrahydro-2H-1,3,5-thiadiazine-2-thione scaffold have found many applications in recent years. This review is aimed at highlighting the most important aspects about these compounds: synthesis, spectroscopic characterization and antiprotozoan activities. How the chemical nature of N-substituents influences the overall activity / cytotoxicity profile will also be discussed.

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