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Microanalysis of lipids in discrete brain areas of the rabbit following intramuscular administration of steroid contraceptive

Authors
Journal
Contraception
0010-7824
Publisher
Elsevier
Publication Date
Volume
21
Issue
4
Identifiers
DOI: 10.1016/s0010-7824(80)80020-5

Abstract

Abstract The effects of 60- and 90-day administration of a pill containing 0.05 mg ethinylestradiol and 0.5 mg norgestrel on the regional lipid levels of female albino rabbit brains have been investigated. Decreared levels of total lipids, phospholipids, cholosterol, free fatty acids and esterified fatty acids were observed in hypothalamus, hippocampus, amygdaloid nucleus, midline nuclei of thalamus and gyrus cinguli. However, the levels of esterified fatty acids only in the amygdaloid nucleus and that of cholosterol in hypothalamus were significantly increased.

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