Abstract The control of haemostasis and tissue sealing are two essential aspects in any surgical procedure. The local haemostatic fibrin sealants help to reduce the risk of bleeding by favouring coagulation. Furthermore, agents such as TachoSil® (TS) have sealant properties that strengthen surgical sutures, particularly vascular, when standard techniques are insufficient. The main objective of this work is to review current scientific evidence on the use of TS in surgical procedures related to vascular surgery. For this purpose, a literature search was conducted using Medline for articles published from January 1987 until March 2011. After methodological evaluation, five preclinical studies and ten clinical studies were included, according to scientific evidence levels. The result of this review shows that TS has haemostatic and vascular suture reinforcement properties. For these reasons, it is useful in surgical procedures with a risk of bleeding and which may require sealing structures.