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Supernumerary isochromosome 4p in ANLL-M4 myelomonocytic type is associated with favorable prognosis

Authors
Journal
Cancer Genetics and Cytogenetics
0165-4608
Publisher
Elsevier
Publication Date
Volume
79
Issue
2
Identifiers
DOI: 10.1016/0165-4608(94)00125-u

Abstract

Abstract A case of an acute non-lymphocytic leukemia of M4 type with a supernumerary isochromosome (4p) in 100% of the initial bone marrow metaphase cells is reported. The origin of the extra chromosome is verified by the fluorescence in situ hybridization technique using a whole chromosome 4 painting probe. A possible favorable prognosis of the ANLL-M4 case showing a supernumerary isochromosome (4p) is cautiously emphasized.

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