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X-ray fluorescence spectroscopic analysis of bromine in pharmaceutical formulations

Authors
Publisher
Institute of Organic Chemistry and Biochemistry
Publication Date
Disciplines
  • Chemistry
  • Pharmacology

Abstract

A fast and accurate method is proposed for the determination of bromine in pharmaceutical formulations. The method is based on the application of X-ray fluorescence spectroscopy to solid samples and can be used for the assay of total bromine in various chemical media. It has high reliability provided that the appropriate matrix effect correction is employed, through the use of the scattered W-line from the X-ray tube as an internal standard.

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