Affordable Access

Comparative methods of detecting HbsAg in chronic glomerulonephritis patients in Nigeria

Authors
Journal
FEMS Microbiology Letters
0378-1097
Publisher
Oxford University Press
Publication Date
Keywords
  • Elisa
  • Passive Haemagglutination
  • Counter Immunoelectrophoresis
Disciplines
  • Biology

Abstract

Abstract A comparative evaluation of the enzyme-linked immunosorbent assay (Elisa), passive haemagglutination (PHA) and counterimmunoelectrophoresis (CIE) methods were carried out. Approx. 6% of control samples were positive with the Elisa assay, while the values for Behring Institute (BI) passive haemagglutination, Wellcome Research Laboratory (WRL) passive haemagglutination and CIE were 2.7%, 2.2% and 3.3%, respectively. The above data contrast with values of 21.3%, 10.6, 10.3 and 12.3 obtained in sera from chronic glomerulonephritis patients. Our observation suggests that HbsAg may be associated with chronic glomerulonephritis.

There are no comments yet on this publication. Be the first to share your thoughts.