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Chemical carcinogenesis in the thyroid gland

Authors
Journal
Toxicology Letters
0378-4274
Publisher
Elsevier
Publication Date
Identifiers
DOI: 10.1016/0378-4274(92)90212-3
Keywords
  • Thyroid
  • Neoplasm
  • Promotion
  • Initiation
  • N-Bis(2-Hydroxypropyl)Nitrosamine

Abstract

Abstract Chemical carcinogens and promoters in thyroid carcinogenesis may be divided into two types, one having goitrogenic effects, the other not having these effects e.g. phenobarbital, 4,4'-diaminodiphenylmethane. The influence of sex hormones like estrogen and testosterone remains unclear, although some thyroid tumors have estrogen receptors. Further studies in this area are necessary.

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