Affordable Access

Publisher Website

Endothelin and the kidney

Elsevier B.V.
Publication Date
DOI: 10.1016/s1569-2590(00)09066-2
  • Medicine


Abstract ET has been shown to exert significant effects on glomerular, tubular, and vascular functions of the kidney. ET receptor subtypes mediating these effects of ET appear to be different in different species. ET production, metabolism as well as ET binding are altered in a number of renal diseases, and ET receptor antagonists as well as antibodies have been shown to be beneficial in these diseases. Although a number of very potent and selective ET receptor antagonists are available, the future challenge lies in our understanding of the subtype of ET receptor that is involved in different disease processes.

There are no comments yet on this publication. Be the first to share your thoughts.


Seen <100 times

More articles like this

[Endothelin (ET) in kidneys].

on Postȩpy higieny i medycyny do... 1994

[Endothelin and kidney].

on Néphrologie 1993

Endothelin in kidney disease.

on Current opinion in nephrology... January 1994

Endothelins in diabetic kidneys.

on Kidney international. Suppleme... September 1995
More articles like this..