Affordable Access

Publisher Website

Endothelin and the kidney

Authors
Publisher
Elsevier B.V.
Publication Date
Identifiers
DOI: 10.1016/s1569-2590(00)09066-2
Disciplines
  • Medicine

Abstract

Abstract ET has been shown to exert significant effects on glomerular, tubular, and vascular functions of the kidney. ET receptor subtypes mediating these effects of ET appear to be different in different species. ET production, metabolism as well as ET binding are altered in a number of renal diseases, and ET receptor antagonists as well as antibodies have been shown to be beneficial in these diseases. Although a number of very potent and selective ET receptor antagonists are available, the future challenge lies in our understanding of the subtype of ET receptor that is involved in different disease processes.

There are no comments yet on this publication. Be the first to share your thoughts.

Statistics

Seen <100 times
0 Comments

More articles like this

[Endothelin (ET) in kidneys].

on Postȩpy higieny i medycyny do... 1994

[Endothelin and kidney].

on Néphrologie 1993

Endothelin-1 and the kidney--beyond BP.

on British Journal of Pharmacolog... October 2012

Endothelin in kidney disease.

on Current opinion in nephrology... January 1994
More articles like this..