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Influence of serum proteins on fructosamine concentration in multiple myeloma

Authors
Journal
Clinica Chimica Acta
0009-8981
Publisher
Elsevier
Publication Date
Volume
204
Identifiers
DOI: 10.1016/0009-8981(91)90223-y
Keywords
  • Multiple Myeloma
  • Serum Proteins
  • Fructosamine
  • Glucose Metabolism
Disciplines
  • Biology

Abstract

Abstract Serum fructosamine levels in 36 subjects with various types of multiple myeloma and in 64 normal controls were evaluated by means of a Nitroblue tetrazolium colorimetric assay. Only the IgA myeloma group showed significantly raised serum fructosamine values ( P<0.001). In the IgG myeloma group, which showed a higher mean serum protein concentration, serum fructosamine levels were not significantly different from controls. The study shows that elevated IgA levels do influence serum fructosamine and this effect should be taken into due consideration in order to avoid possible misinterpretations in evaluating this widely used index of glucose metabolism.

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