Minimizing negative impacts associated with water rebound in decommissioned mines requires a quantitative assessment of the process. An innovative modeling approach has been developed to simulate mine water rebound, where three-dimensional flow in fractured rock is fully coupled to one-dimensional flow occurring inside mine conduits. This approach has been tested against a documented case of mine water rebound at the Saizerais mine, in northeastern France. The model adequately reproduces the temporal evolution of hydraulic head inside the mine during and after rebound, as well as trends of water overflow at the ground surface. Overestimation of overflow discharge by the model suggests that the fractured rock units adjacent to the mine do not behave as equivalent porous media.