Affordable Access

Publisher Website

Preimplantation and postimplantation therapy for the treatment of reproductive failure

Authors
Journal
Journal of Human Reproductive Sciences
0974-1208
Publisher
Medknow Publications
Publication Date
Volume
6
Issue
2
Identifiers
DOI: 10.4103/0974-1208.117165
Keywords
  • Review Article
Disciplines
  • Medicine

Abstract

Treatment of patients with recurrent pregnancy losses and recurrent implantation failure can be instituted only when the underlying etiology is determined. Embryo-secreted preimplantation factor (PIF) is essential for implantation and adequate trophoblastic invasion. Deficiency of PIF affects the outcome of the pregnancy leading to recurrent pregnancy losses. Synthetic PIF modulates the outcome of the pregnancy decreasing the incidence of recurrent implantation failure and recurrent pregnancy losses. In this article a thorough search is done regarding the data published for diagnoses of reproductive failure and its treatment. The effect of immunoglobulin (Ig), intralipid, heparin, aspirin, progesterone, estrogen, and granulocyte colony stimulating factor (G-CSF) is taken into consideration. Heparin, aspirin, and progesterone have successfully shown to decrease the incidence of recurrent pregnancy loses; whereas G-CSF, intralipids, estrogen, and Igs have shown success in the treatment of the recurrent implantation failure and recurrent pregnancy failure. The pregnancies treated with Igs and intralipids showed equal outcome when evaluated and compared. The place of intralipid in reducing natural killer (NK) cells has been discussed.

There are no comments yet on this publication. Be the first to share your thoughts.

Statistics

Seen <100 times
0 Comments

More articles like this

Effect of maternal age on postimplantation reprodu...

on Journal of reproduction and fe... March 1971

Growth hormone therapy as a treatment for heart fa...

on Evidence-based cardiovascular... June 2006

Treatment Failure in Dialectical Behavior Therapy

on Cognitive and Behavioral Pract... Jan 01, 2011

Nonadherence to asthma treatment and failure of th...

on Current opinion in pediatrics December 1997
More articles like this..