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Towards coronary flow assessment by a wire-tip pressure sensor

Authors
Publisher
Technische Universiteit Eindhoven
Publication Date
Disciplines
  • Medicine

Abstract

ARK 2000 WTB 2000033 . U niversity of Technology vepartment of Mechanical Engineering Section Materials Technology Towards coronary flow assessment by a wire-tip pressure sensor M.A.Terlouw MaTe-report MT 00.033 Under supervision of: F .P. T. Baaijens N.H.J.Pijls Coach: F.N. van de Vosse TUle Eindhoven University of Technology, 21st November 2000 Contents Summary 1 Introduction 2 Background of the project 2.1 The eoronary cireulation . 2.2 Catheterisation ..... . 2.3 Fraetional Flow reserve (FFR) 2.4 Microvaseular diseases 2.5 The pressure wire . 3 Theory 3.1 The boundary-Iayer theory 3.2 Global analysis Uni-axial flow through an annulus 3.2.1 The Boussinesq approximation 3.2.2 Sealing analysis . . . . . . 3.3 Loeal analysis A heated eavity, driven by shear 3.3.1 Sealing analysis . 3.4 Zero order model . . . . . . . . . 4 The numerical model 4.1 Spatial diseretisation 4.2 Temporal diseretisation 5 Validation of the numerical model 5.1 Mixed eonveetion in the lid driven eavity ..... . 5.2 The heated eavity problem ............ . 5.3 The heat transfer of a (partially) heated flat plate 6 Results and discussion 6.1 Computation of the shear rate 6.1.1 Results ........ . 6.2 Computation of the heat transfer 6.2.1 Results .. 6.2.2 Diseussion. 6.3 Diffusion...... 6.3.1 Results .. 6.3.2 Diseussion. 2 4 5 6 6 7 8 9 10 11 11 13 13 14 16 16 17 19 19 21 22 22 23 26 29 29 30 31 32 33 37 37 37 7 Conclusions and recommendations 7.1 Conclusions .... 7.2 Recommendations Bibliography Samenvatting A List of symbols B Material properties C The Wheatstone bridge D The Boussinseq approximation E The finite element formulation F The theta-method G Heat transfer in laminar flow G.1 The momentum equation of the boundary layer G.2 The heat-flow equation of the boundary layer G.3 Heat transfer ...... . G.4 Non-uniform heated plate .....

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