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Serum vitamin A and vitamin E concentrations after parenteral vitamin A administration in sheep

Authors
Journal
Small Ruminant Research
0921-4488
Publisher
Elsevier
Volume
109
Issue
1
Identifiers
DOI: 10.1016/j.smallrumres.2012.07.015
Keywords
  • Vitamin A
  • Vitamin E
  • Sheep
  • Kinetics
  • Parenteral Injection

Abstract

Abstract Twenty primiparous dairy sheep of the Mytilene breed, which were fed with a ration deficient in vitamin A and carotenes, were divided into 2 groups of 10 animals each after a 2-month adaptation period. The animals of group A were administered vitamin A palmitate by intramuscular injection (3500IU/kgbodyweight), while the animals of group B were used as controls and received only the vehicle of the preparation without vitamin A. Serum vitamin A concentrations increased significantly in the animals of group A compared to the animals of group B (P<0.01) from the first 24h post-injection and remained significantly high for 8 days, and at 10 days post-injection they reached the pre-injection levels. The serum vitamin E concentration declined significantly (P<0.05) in the animals of group A compared to the animals of group B for 8 days, when they reached the pre-injection levels. No changes in serum vitamins A and E levels in the animals of the 2 groups were observed 20 days after the injection of vitamin A.

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