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A 5'-proximal stem-loop structure of 5' untranslated region of porcine reproductive and respiratory syndrome virus genome is key for virus replication.

Authors
  • Lu, Jiaqi
  • Gao, Fei
  • Wei, Zuzhang
  • Liu, Ping
  • Liu, Changlong
  • Zheng, Haihong
  • Li, Yanhua
  • Lin, Tao
  • Yuan, Shishan
Type
Published Article
Journal
Virology Journal
Publisher
Springer (Biomed Central Ltd.)
Publication Date
Jan 01, 2011
Volume
8
Pages
172–172
Identifiers
DOI: 10.1186/1743-422X-8-172
PMID: 21496223
Source
Medline
License
Unknown

Abstract

Taken together, we concluded that the phylogenetically conserved SL2 in the 5' UTR was crucial for PRRSV virus replication, subgenomic mRNA synthesis in particular.

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