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[5-aminosalicylic acid for induction of remission or clinical response in Crohn's disease--a survey of a Cochrane review].

Authors
Type
Published Article
Journal
Ugeskrift for laeger
1603-6824
Publication Date
Volume
173
Issue
35
Pages
2110–2113
Identifiers
PMID: 21884660
Source
Medline
License
Unknown

Abstract

A systematic review to evaluate the efficacy of 5-aminosalicylates for induction of remission or clinical response in patients with mild to moderately active Crohn's disease is described. The effect of either high (3 to 4.5 g/day) or low dose (1 to 2 g/day) 5-aminosalicylic acid was similar to that of placebo. Overall, sulfasalazine was not superior to placebo and was inferior to glucocorticoids for the treatment of mild to moderately active Crohn's disease. Neither published nor unpublished data support any use of 5-aminosalicylates for the treatment of Crohn's disease.

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