Potent antagonists at the glycine-binding site of NMDA receptors, as well as dual antagonists acting also at AMPA receptors have been identified in a series of 5-arylaminomethylquinoxaline-2,3-diones. A study of the structure-activity relationship of these compounds is reported here.
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The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/9871631