Affordable Access

Publisher Website

Catalytic triple carbonylation of olefins. Enantioselective synthesis of 2-oxoglutarates

Authors
Journal
Journal of Organometallic Chemistry
0022-328X
Publisher
Elsevier
Publication Date
Volume
506
Identifiers
DOI: 10.1016/0022-328x(95)05654-8
Keywords
  • Enantioselective Catalysis
  • Triple Carbonylation
  • Olefins
  • Palladium Complexes
  • 2-Oxoglutarates

Abstract

Abstract A new carbonylation reaction, namely “triple carbonylation” of olefins catalysed by cationic palladium complexes to substituted 2-oxoglutarates, has been developed. Even though the chemoselectivity is not high, this reaction allows a one-step synthesis of substituted 2-oxoglutarates with fair to excellent enantioselectivity (enantiomeric excess up to 92%). The reaction is completely regioselective for styrene whereas with aliphatic olefins two regioisomers are formed.

There are no comments yet on this publication. Be the first to share your thoughts.

Statistics

Seen <100 times
0 Comments