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Successful management of a triplet heterotopic caesarean scar pregnancy after in vitro fertilization-embryo transfer

Authors
Journal
Fertility and Sterility
0015-0282
Publisher
Elsevier
Publication Date
Volume
95
Issue
1
Identifiers
DOI: 10.1016/j.fertnstert.2010.05.025
Keywords
  • Caesarean Scar Pregnancy
  • Heterotopic Pregnancy
  • Embryo Reduction
  • Potassium Chloride
  • Methotrexate
Disciplines
  • Ecology
  • Medicine

Abstract

Objective To report a case of a triplet heterotopic caesarean scar pregnancy (CSP) with two gestational sacs implanted in the caesarean scar after in vitro fertilization-embryo transfer. Design Case report. Settings Private reproductive medicine center and obstetric department of a university hospital. Patient(s) A 31-year-old woman with previous caesarean section affected by secondary infertility related to male azoospermia. Intervention(s) In vitro fertilization-embryotransfer followed by early ultrasound diagnosis of heterotopic CSP and selective embryo reduction performed by transvaginal ultrasound-guided potassium chloride and methotrexate injection in the ectopic gestational sacs. Main outcome mesure(s) Successful pregnancy outcome. Result(s) An ongoing intrauterine pregnancy with a live birth after successful management of ectopic gestational sacs. Conclusion(s) Triplet heterotopic CSP with two ectopic gestational sacs may occur after IVF-ET and, to our knowledge, this is the first time such a complication has been reported. Ultrasound is the main tool allowing early diagnosis of this condition, and the injection of potassium chloride and methotrexate is a safe and efficacious treatment method. The gynecologist managing early pregnancy should be aware of the possibility of CSP, and patients must be appropriately counseled about the different treatment options.

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