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Host Tolerance versus Resistance and Microbial Virulence in the Host-Pathogen Equation

Authors
Journal
Cell Host & Microbe
1931-3128
Publisher
Elsevier
Publication Date
Volume
6
Issue
3
Identifiers
DOI: 10.1016/j.chom.2009.08.010

Abstract

To deal with an infection, the organism resorts to nonmutually exclusive strategies: resistance, that is, neutralization or destruction of the pathogen; or tolerance, the ability to withstand damages inflicted by the pathogen or by host defense. In this issue of Cell Host & Microbe, Shinzawa et al. (2009) identify p38-mediated phagocytic encapsulation as a potential tolerance mechanism.

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