Affordable Access

Comparative bioavailability: Eight commercial prednisone tablets

Journal of Pharmacokinetics and Biopharmaceutics
Publication Date


Two four-treatment crossover bioavailability studies were performed in panels of 12 adult male volunteers with eight different commercial prednisone tablets. Plasma samples from the first study were assayed by radioimmunoassay for both prednisone and prednisolone. Plasma samples from the second study were assayed for prednisolone only. Statistical analyses of the data showed significant differences in the rate of appearance of prednisolone in plasma, but not in the amount convened to prednisolone. Some observations are made on the relationships between prednisone and prednisolone concentrations in plasma following oral administration of prednisone .

There are no comments yet on this publication. Be the first to share your thoughts.


Seen <100 times

More articles like this

Comparative bioavailability: eight commercial pred...

on Journal of pharmacokinetics an... April 1976

[Comparative bioavailability of prednisone and pre...

on Sichuan yi xue yuan xue bao =... September 1985

Comparative bioavailability of three commercial ac...

on International journal of clini... February 1987

Comparative bioavailability of two commercial prep...

on European Journal of Clinical P... July 1979
More articles like this..