Abstract 1. 1. Isoprene content in products of dehydrogenation of 3-methylbut-1-ene using a palladium alloy with 5·9% nickel under pulse conditions exceeds its content in products of dehydrogenation of 2-methylbut-1-ene and 2-methyl-but-2-ene. The reaction is of first order in terms of the initial material, apparent activation energy being 9 kcal/mole. 2. 2. Under optimum conditions dehydrogenation of isoamylenes, when the hydrogen is removed through a membrane catalyst, is also of first order in terms of the initial material. With an increase in the partial pressure of isoamylenes, the isoprene content of the products decreases and the efficiency of unit catalyst surface increases to 10 g isoprene every 1 m 2/hr. 3. 3. In a large all-metal reactor with a membrane catalyst of a palladium nickel alloy, isoprene content in products of dehydrogenation of isoamylenes reaches 54% per pass.