Affordable Access

Publisher Website

Novel method for preparing bis(trimethylsilyl) amines via treatment with trimethylsilylamines and methyl iodide

Authors
Journal
Journal of Organometallic Chemistry
0022-328X
Publisher
Elsevier
Publication Date
Volume
510
Identifiers
DOI: 10.1016/0022-328x(95)05821-6
Keywords
  • Silicon
  • Trimethylsilyl
  • N-(Trimethylsilyl)Diethylamine
  • Bissilylation
  • Bis(Trimethylsilyl)Amine

Abstract

Abstract A convenient method for the synthesis of N,N-bis(trimethylsilyl)alkylamines has been reported. N-(Trimethylsilyl)diethylamine incorporated with a stoichiometric amount of methyl iodide was effective to convert primary amines, especially aromatic amines, and their monotrimethylsilyl derivatives into the corresponding N,N-bis(trimethylsilyl)amine derivatives in high yields. In the case of N-trimethylsilyl derivatives of aliphatic primary amines, a half-amount of silylamines served as a silylation agent against another half-amount of silylamines in the presence of 0.5 equivalent of methyl iodide to give N,N-bis(trimethylsilyl)alkylamines in good yield. Allyl iodide, allyl bromide and benzyl bromide were also effective to promote the silylation activity of silylamines.

There are no comments yet on this publication. Be the first to share your thoughts.