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An improved procedure for the synthesis of oxindole-3-carbinol (hydroxymethyl oxindole)

Authors
Journal
Phytochemistry
0031-9422
Publisher
Elsevier
Publication Date
Volume
10
Issue
7
Identifiers
DOI: 10.1016/0031-9422(71)85022-7
Disciplines
  • Chemistry

Abstract

Abstract Oxindole-3-carbinol was synthesized by the photochemical oxidation of 3-indoleacetic acid. The reaction was performed in buffered aqueous solution at pH 4·6 in the presence of riboflavin and using fluorescent lamps as an energy source. The molar extinction coefficient of oxindole-3-carbinol in 95% ethanol was determined to be 21,300.

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