Increasing competition among Latin American firms fosters more proactive processes aimed at reviewing business strategy. The research objective is to measure the impact of key variables on successful implementation of business strategy. Relying on the knowledge and experience of Latin American entrepreneurs and managers, the questions addressed include: How important is the role of the CEO and management actors? Do firms prioritize actions prior to implementing strategy? Are control and follow-up tools valued? How is a successful strategy implementation ensured? Research findings are expected to provide useful knowledge for management decision processes relating to successful implementation of business strategy.