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Efficacy of mupirocin nasal ointment in eradicatingStaphylococcus aureusnasal carriage in chronic haemodialysis patients

Authors
Journal
Journal of Hospital Infection
0195-6701
Publisher
Elsevier
Publication Date
Volume
17
Issue
2
Identifiers
DOI: 10.1016/0195-6701(91)90177-a
Keywords
  • Mupirocin
  • Haemodialysis
  • Staphylococcus Aureus
  • Nasal Colonization
Disciplines
  • Medicine

Abstract

Abstract Topical 2% mupirocin ointment eradicated chronic Staphylococcus aureus nasal carriage immediately post-therapy in 17 (77%) of 22 haemodialysis patients. Mean time to recurrence was 3·8 weeks. Similar pretherapy and post-therapy phage types occurred in 12 (71%) of 17 patients. Staphylococcus aureus infections developed in none of 17 successfully treated patients, two of five treatment failures ( P = 0·05), and 10 of 46 untreated patients studied concurrently ( P = 0·03).

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