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An allosteric mechanism for the acetylcholine receptor

Authors
Journal
Biochemical and Biophysical Research Communications
0006-291X
Publisher
Elsevier
Publication Date
Volume
48
Issue
5
Identifiers
DOI: 10.1016/0006-291x(72)90832-7

Abstract

Abstract The excitable membrane of electroplax is depolarized to different maximal extents with different triggering ligands. The extent of depolarization is also altered by inhibitors. These properties are interpreted in terms of a simple and quantitative molecular mechanism based on the state function of the allosteric model.

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