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Effects of cocaine on heart rate variability in healthy subjects

Authors
Journal
The American Journal of Cardiology
0002-9149
Publisher
Elsevier
Publication Date
Volume
93
Issue
3
Identifiers
DOI: 10.1016/j.amjcard.2003.10.028

Abstract

Abstract In this study, we found that cocaine decreased the high-frequency power of heart rate variability in normal volunteers, implicating a decrease in vagal tone. However, the results of our autonomic blocking studies indicated the opposite, suggesting a major influence of cardiac sympathetic drive on the high-frequency power of heart rate variability.

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