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A tandem Baylis–Hillman-singlet oxygen oxidation reaction for facile synthesis of γ-substituted γ-hydroxybutenolides

Authors
Journal
Tetrahedron
0040-4020
Publisher
Elsevier
Publication Date
Volume
64
Issue
48
Identifiers
DOI: 10.1016/j.tet.2008.09.019

Abstract

Abstract A series of highly functionalised γ-hydroxyacryl γ-hydroxybutenolides, 2, were synthesised in 25–50% overall yields in two or three steps from 2-furfural using a tandem Baylis–Hillman-singlet oxygen oxidation reaction.

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