The purpose of this paper is to describe and compare key dimension of the business incubation landscape in the United States. The comparison will focused on the five key dimensions which include incubators services provided by incubators to client firms, strategic goals, incubators’ sponsors, incubators age and incubators focus. The nature of this research is mainly qualitative. This investigation uses two semi-structured interviews based in the United States and organizational documents. The research findings suggest that there are three keys. The authors believe that, this paper presents an added value to the current literature on the key dimension of business incubation in the United States. Also the research will support the academia and practitioner for successful implementations and follow-up. Keywords: Jobs creation, technology commercialization, entrepreneurship, incubators, economic growth.