Abstract The lymph circulation plays an important role in interstitial fluid balance, protein transport, and immune system. However, its mechanism is poorly understood, and associated pathologies are mostly untreatable. By following Sungawa's method of discussing the heart output, a hemodynamic model of lymph circulation was set up. The model was used to demonstrate how the lymphatic fluid formation, investigate the relationship between the lymph flow rate Q L and physiological parameters, and explore how local massage influences Q L Computer simulation results show that Q L is linearly proportional to the interstitial fluid pressure P i , which is similar to experimental observations. Comparing the simulated value of Q L during the massage of different frequency with the experimental data from Ikomi shows that they are identical, which indicates that the presented model is rational to explain the mechanism of massage treatment in traditional Chinese medicine (TCM).