Affordable Access

Publisher Website

The effect of aflatoxin B1on the maturation of ribosomal and transfer RNA in monkey kidney (CV-1) cells in culture

Authors
Journal
Chemico-Biological Interactions
0009-2797
Publisher
Elsevier
Publication Date
Volume
9
Issue
6
Identifiers
DOI: 10.1016/0009-2797(74)90024-6

Abstract

Abstract Aflatoxin B 1 has been found to inhibit the maturation of rRNA by causing a build-up of 32S RNA in the nucleolus associated with reduced output of 28S rRNA to the cytoplasm. Processing of 18S rRNA appears normal. Other experiments on the maturation of tRNA have shown that again aflatoxin B 1 delays the processing of the precursor. The mechanism of action of the toxin and the relationship between these results and the observed inhibition of transcription are discussed.

There are no comments yet on this publication. Be the first to share your thoughts.

Statistics

Seen <100 times
0 Comments

More articles like this

The effect of aflatoxin B, on the maturation of ri...

on Chemico-Biological Interaction... December 1974

Effects of mycotoxins in cultured kidney cells: Cy...

on Ecotoxicology and Environmenta... Jan 01, 1987

The effect of aflatoxin B1on translation in cells...

on Chemico-Biological Interaction... Jan 01, 1980

The effect of aflatoxin B1 on translation in cells...

on Chemico-Biological Interaction... October 1980
More articles like this..