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ФУНКЦИОНАЛЬНОЕ СОСТОЯНИЕ ЭНДОТЕЛИЯ СОСУДОВ И ТРОМБОЦИТОВ У ЖЕНЩИН С ЭССЕНЦИАЛЬНОЙ АРТЕРИАЛЬНОЙ ГИПЕРТЕНЗИЕЙ В ПОСТМЕНОПАУЗЕ НА ФОНЕ КОМБИНИРОВАННОГО ПРИМЕНЕНИЯ АЦЕТИЛСАЛИЦИЛОВОЙ КИСЛОТЫ И КЛОПИДОГРЕЛЯ

Authors
Publisher
Филиал Открытого акционерного общество «Татмедиа» «Редакция «Казанского медицинского журнала»
Publication Date
Disciplines
  • Biology
  • Pharmacology

Abstract

Concentrations of von Willebrand factor, beta-thromboglobulin and 4th platelet factor were assessed in 170 women in postmenopause, which were divided into two groups depending on the degree of essential arterial hypertension, treated by the combination of acetylsalicylic acid and clopidogrel. The changes of markers of functional activity of platelets and markers of endothelial dysfunction indicate the possibility of pharmacological reduction of platelet activation in order to prevent thrombotic episodes in patients with arterial hypertension.

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